STING (stimulator of interferon genes) is a key mediator of innate immunity and the STING pathway has been shown to be involved in the induction of an anti-tumor immune response. We recently spoke to Andrea van Elsas, PhD, Chief Scientific Officer at Aduro Biotech to learn more about the company’s expertise in STING Pathway Activator technology.Read More
The Defense Advanced Research Projects Agency’s (DARPA) Synergistic Discovery and Design Program (SD2) hopes to update protocols with enhanced automation and machine learning strategies. As part of SD2, Ginkgo Bioworks, and Transcriptic have been offered a dual contract to help advance biological experimentation and iterative testing for synthetic biology. In this blog, we discuss the goals of SD2 and the impact of automation on research with Ben Miles, PhD, Head of Product at Transcriptic.Read More
We recently spoke to Stanislas Veillet, Chairman and CEO of Biophytis to learn more about the company’s efforts to develop first-in-class drugs to treat degenerative illnesses associated with aging.Read More
During this year’s AACR Annual Meeting we spoke to Julianna Supplee, Research Technician at the Robert and Renée Belfer Center for Applied Cancer Science at Dana-Farber Cancer Institute, to learn more about the team’s most recent study on the use of plasma HPV cell-free DNA as an early predictor of treatment response in patients with advanced oropharyngeal cancer.Read More
Digital transformation, often described as the next industrial revolution, has already begun to permanently change almost every aspect of our lives.
Science, of course, is no exception. Digital transformation is poised to fundamentally change how scientists conduct research and how laboratories operate. But, what is the current state of digitalization within today’s labs, and how can they ensure they are ready for digital transformation?
During this year’s AACR conference we spoke to Kang Zhang, M.D., Ph.D. from the University of California, San Diego about the collaborative work he has been doing with the Laboratory for Advanced Medicine. He discusses their recent study findings on the use of a blood-based method to look at cell-free DNA as a marker for liver cancer diagnosis and prognosis.Read More
Understanding the proteome is a fundamental challenge of biology. Here, Bruker Daltonics' Gary Kruppa and Scarlet Koch outline a new method, Parallel Accumulation Serial Fragmentation (PASEF) that offers faster, more sensitive and more robust proteome analysis, giving scientists the potential to discover low-level, biologically significant proteins and validate them in research.Read More
Pesticides are widely used to protect food crops from damage and consequently have the potential to end up in the food we eat. Young children and babies can be particularly susceptible to pesticide residues in food so testing for pesticide residues in food, and baby food in particular, is therefore critical for the preservation of human health.Read More
Genomic Profiling in Cancer: Matching Patients to Precision Trials, Guiding Patients to the Right TreatmentBlog
We recently spoke to Gaurav Singal, Vice President of Data Strategy and Product Development at Foundation Medicine, to learn more about how their SmartTrialsTM technology platform has enabled patients to be rapidly matched to precision trials, based on their unique tumor biomarkers.Read More
As the research landscape changes, the standards of data integrity that guide research must also change. New data tools, systems and formats provide pitfalls and opportunities for advancing the cause of data integrity. In this blog, we discuss integrity in modern research with John Sadler, Vice President and General Manager of Agilent’s Software & Informatics Division.Read More