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PAT-Enabled Scaling and Optimization of Upstream Bioprocesses

Scientist in sterile protective gear operating bioprocessing equipment in a cleanroom laboratory
Credit: iStock

Scaling up a bioprocess is a complex, multi-variable challenge. Designing processes with scalable parameters is essential for ensuring confidence when transitioning from the research laboratory to clinical and production operations.

The application notes in this compendium show how modern bioreactors and process Raman technology can enhance bioprocess development and enable advanced process control strategies from pilot to production scale.