Circulating Tumor Antigens and their Autoantibody Reactivity as Cancer Markers
Conference Recording Aug 01, 2013
About the Speaker
Dr. Hanash is program head for Molecular Diagnostics at the Fred Hutchinson Cancer Research Center in Seattle, Washington. Dr. Hanash’s interests and expertise focus on the development and application of integrated approaches to the molecular profiling of cancer, with particular emphasis on proteomics. He has been a program principal investigator for several multi-investigator projects aimed at biomarker discovery and validation using proteomics. Dr. Hanash has organized and participated in several workshops and initiatives related to diagnostics and proteomics. He is the inaugural president of the Human Proteome Organization.Abstract
The dynamic shedding of proteins and antigens from tumor cells offers an opportunity to develop cancer markers based on the detection of such proteins and the immune response they engender in the form of autoantibodies.