Accelerate Your PROTACs Drug Discovery and Development

Emerging therapeutic modalities like proteolysis targeting chimeras (PROTACs) have opened the door to previously "undruggable" targets, but their complex, bifunctional structure makes them notoriously difficult to characterize and quantify at the low concentrations.

Progressing PROTACs molecules from discovery to development requires an optimized analytical toolset and informatics ecosystem that provide critical insights across all aspects of DMPK.

This eBook shows how an integrated, end-to-end analytical approach helps labs generate reliable, regulatory-ready data at every stage of discovery & development for PROTACs.

In this eBook, you'll learn how to: 

• Improve recovery and reduce matrix effects during PROTAC sample preparation 
• Achieve picogram-level sensitivity for low-abundance PROTAC quantification 
• Characterize PROTAC metabolites and visualize tissue distribution with confidence