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Understanding Tumor Microenvironment Signaling Pathways

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Understanding Tumor Microenvironment Signaling Pathways and Attempts To Target Components in Solid Cancer Therapy


The tumor microenvironment (TME) is comprised of the tumor, extracellular matrix and various non-transformed cells including fibroblasts, immune infiltrates and vascular vessels. TME plays a key role in tumor initiation, progression, invasion, metastasis and resistance. Understanding TME requires close examination of signaling pathways responsible for its characteristics.


Download this eBook to learn more about:

  • Receptor tyrosine kinase signaling
  • Cytokine receptors
  • Ancient signaling