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University of Hull

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Content Written By, Reviewed By, or Featuring Amy Dawson

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Video

A Microfluidic Chip based Model for the Study of Full Thickness Human Intestinal Tissue

A dual-flow microfluidic device has been optimised to hold human gut biopsies in a known orientation mimicking the biomimetic environment, with continual media perfusion and simultaneous waste removal. Characterisation of the tissue by measuring cell death, proliferation, histology and soluble inflammatory biomarkers has shown that it remains viable and functional.

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