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A picture of Dr. Sigrid Nachtergaele

Dr. Sigrid Nachtergaele profile page

Assistant Professor of Molecular, Cellular, and Developmental Biology

 at Yale University


Sigrid Nachtergaele received her undergraduate degree from the University of Chicago and her PhD from Stanford University. During her graduate work in the laboratory of Rajat Rohatgi, she developed novel chemical tools to study Hedgehog signaling, uncovering new modes of sterol-mediated regulation of this critical developmental pathway. She was a postdoctoral fellow with Chuan He at the University of Chicago, where she set out to identify novel chemical modifications in mRNA and uncover their functions. While these modifications are known to influence RNA processing, stability, and function, much less is known about how these modifications are regulated by and influence cell signaling. Her lab at Yale is focused on identifying these mechanisms, with the goal of identifying new modes of RNA-mediated regulation of cell signaling. She was awarded a Damon Runyon Postdoctoral Fellowship and subsequently a Damon Runyon Dale F. Frey Award for Breakthrough Scientists for this work.


Education


Stanford University  

University of Chicago  


Awards & Certifications


Damon Runyon Postdoctoral Fellowship

a Damon Runyon Dale F. Frey Award for Breakthrough Scientists


Areas of Expertise



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