Assistant Professor of Molecular, Cellular, and Developmental Biology
at Yale University
Sigrid Nachtergaele received her undergraduate degree from the University of Chicago and her PhD from Stanford University. During her graduate work in the laboratory of Rajat Rohatgi, she developed novel chemical tools to study Hedgehog signaling, uncovering new modes of sterol-mediated regulation of this critical developmental pathway. She was a postdoctoral fellow with Chuan He at the University of Chicago, where she set out to identify novel chemical modifications in mRNA and uncover their functions. While these modifications are known to influence RNA processing, stability, and function, much less is known about how these modifications are regulated by and influence cell signaling. Her lab at Yale is focused on identifying these mechanisms, with the goal of identifying new modes of RNA-mediated regulation of cell signaling. She was awarded a Damon Runyon Postdoctoral Fellowship and subsequently a Damon Runyon Dale F. Frey Award for Breakthrough Scientists for this work.
Education
Awards & Certifications
Damon Runyon Postdoctoral Fellowship
a Damon Runyon Dale F. Frey Award for Breakthrough Scientists
Areas of Expertise
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