Dr. Grace Gong profile page

I completed my PhD at The University of Auckland, New Zealand, focusing on designing and characterising small molecule inhibitors that target the PI3-Kinase signalosome. This involved a range of biochemical and biophysical assays, structure-based ligand design, virtual screening, and cellular assays. I then joined Prof. Bart Vanhaesebroeck’s laboratory to work on small molecule modulators of PI3-Kinase, and received a Marie Skłodowska-Curie Personal Fellowship to support this work. My current work focuses on characterising these small molecule modulators with biochemical and structural approaches, and trying to understand how they modulate enzyme structure and activity.