Jessica Woodley, MS
Molecular Genetics Research Group
An Improved Solution for Generating Large CRISPR HDR Knock-Ins
CRISPR-based homology-directed repair (HDR) is an invaluable tool to facilitate specific mutations in a genomic region of interest in research studies. While many methods have been reported for improving HDR efficiency, achieving precise changes via HDR remains a challenge, particularly for large knock-ins.