Khaled Abdelrahman, PhD profile page

Dr. Khaled Abdelrahman is an assistant professor at the University of British Columbia and a principal investigator at the Djavad Mowafaghian Centre for Brain Health, where he leads a rapidly growing and well-funded research program focused on the role of G protein–coupled receptor (GPCR) signaling in neurodegenerative diseases. His work is centered on Alzheimer’s disease, where he investigates how dysregulated GPCR signaling contributes to impaired neurovascular coupling, altered cerebral blood flow, neuroinflammation, and the progression of amyloid and tau pathology. His research aims to identify novel therapeutic targets that can slow or modify disease progression. Abdelrahman completed his PhD in pharmacology at the University of Calgary, followed by postdoctoral training in neuropharmacology at the University of Ottawa. In addition to his academic training, he brings over a decade of experience as a licensed pharmacist, providing him with a unique translational perspective that bridges mechanistic discovery with clinical relevance and patient care. Since establishing his independent program, Abdelrahman has secured substantial and highly competitive funding. Beyond his research program, Abdelrahman has demonstrated strong leadership in mentorship and training. Many members of his research team, from postdoctoral fellows to undergraduate trainees, have received competitive scholarships and presented their work at national and international conferences. Abdelrahman currently serves as chair of the scientific program committee for the Canadian Society of Pharmacology and Therapeutics and contributes to multiple committees within the American Society for Pharmacology and Experimental Therapeutics. Additionally, he organizes workshops and public-facing initiatives to raise awareness of Alzheimer’s disease and connect research with patients and care partners.