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Rob van Montfort profile page

The Institute of Cancer Research

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Content Written By, Reviewed By, or Featuring Rob van Montfort

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Video

Discovery of Potent and Selective Inhibitors of Monopolar Spindle 1 (MPS1) Kinase

This talk presents the discovery and optimization of potent and selective MPS1 inhibitors based on the 1H-pyrrolo[3,2-c]pyridine scaffold, guided by structure-based design and cellular characterization of MPS1 inhibition.

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