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Ruairi J MacKenzie

Science Writer

@rjmsci

Writes for:

Informatics Neuroscience

Latest Content From Ruairi J MacKenzie

ELN, LIMS, CDS, LES: What’s the Difference?
Article

In this article, we look at the key differences between four common types of informatics systems. CSols Inc. is an independent informatics consultancy, and their Delivery Manager, Geoff Turnbull, will help us answer some important questions on the role these systems play, where they overlap with each other, and why we don’t just have one overarching system to rule them all.

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Top 10 Neuroscience News Stories of 2018
List

2018 has been a massive year for neuroscience research. In this list we look at 10 of the most important stories in neuroscience from the last year, touching on spinal cord regeneration, brain organoids, mind-manipulating microbes and the discovery of an entirely new type of brain cell. Here's to another huge year in 2019!

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How to Get Your Data Systems Ready for Inspection
Infographic

Data integrity and correct data governance has been brought into the spotlight by regulators in recent years. Having your data systems inspected can be a stressful and scary experience, but things will go smoothly if prior steps are taken to ensure your data systems are up to scratch before the auditors take a look. In this infographic, we look at the key steps you should take to prepare your data for inspection.

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A (Lab)Step Towards Reproducible Science
Article

The reproducibility crisis is holding back science. London-based Labstep, a start-up out of Oxford University, think that their tool can help make science more open and reproducible. That claim has now been given some concrete evidence with the announcement that the research contingent of the MRC Unit The Gambia at LSHTM will be trialling Labstep across their Banjul-based facility.

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Assembling the Pieces of the Genomic Puzzle
Blog

OmniTier Inc.’s new bioinformatics platform, CompStorTM Novos, takes a de novo assembly-based variant calling approach to the challenge of whole genome sequencing. We caught up with Jon Coker, Omnitier’s CTO, to discuss how this approach matches up to rival techniques, and how high-performance computing approaches like Omnitier’s hope to bring personalized medicine a step closer and boost biology in coming years.

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Single-Cell DNA Sequencing Weaves a Way Towards Personalized Cancer Treatment
Article

High-throughput single-cell analysis has been regularly acclaimed as a transformative technology for sequencing and a huge step towards the goal of personalized medicine. Will Tapestri, a sequencing platform developed by Mission Bio, be the game-changer in DNA analysis we have been waiting for?

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Inflamyloid: What Is It and Why Is It Important in Alzheimer's Disease?
Article

Alzheimer’s disease (AD) is the leading cause of dementia worldwide. Classically, the “amyloid” hypothesis, which ties the disease’s spread to that of amyloid protein, is thought to underlie AD’s pathology. After years of mixed to negative results in clinical trials, new research is underway to investigate what role the brain’s own immune system plays in amyloid-driven disease; an “infl-amyloid” hypothesis.

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How Machine Learning Can Power Drug Discovery
Blog

A recent assessment of the success of the drug development process put the percentage of phase I programs that make it to approval at 13.8%. That figure points to a crisis of attrition within the industry. Netramark, a Toronto-based start-up claim they have a machine learning-powered solution to that crisis

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A Solution to the 'Cocktail Party' Problem
Blog

Loud background noise doesn’t just annoy people by getting in the way of good conversation – it also affects voice activated devices. AudioTelligence, a start-up based out of Cambridge, say they have developed the world’s first digital solution to this ‘cocktail party problem’.

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The Genetics of Coffee Consumption
Article

Marilyn Cornelis, of the Feinberg School of Medicine at Northwestern University, has spent years researching how coffee affects our body. In this interview, she explains how coffee affects our brain, interacts with cannabis, and why listening to your body might be the best way to decide how much coffee to drink.

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