Simone Sidoli, PhD profile page

Dr. Simone Sidoli is an associate professor of biochemistry and genetics at the Albert Einstein College of Medicine and scientific director of the Proteomics Core. His research focuses on developing biochemical and mass spectrometry–based approaches to uncover mechanisms of chromatin regulation, with particular emphasis on chromatin decondensation during aging and cellular heterogeneity at single-cell resolution. His laboratory integrates 3D cell culture models, advanced proteomics workflows, and clinical collaborations, including studies on centenarian and ultracentenarian cohorts. Sidoli maintains a diversified funding portfolio spanning NIH, international foundations, and industry partnerships, and has contributed to the development of single-cell proteomics technologies in academia.