Vivian Li, PhD profile page

Vivian Li is a senior group leader and assistant research director at the Francis Crick Institute. She is a stem cell and cancer biologist who is known for her work on the fine-tuning of Wnt signalling pathway in intestinal stem cells, regeneration and cancer. Her lab combines genetically engineered mouse models, patient-derived organoids, and advanced genomic tools to investigate how Wnt signalling and cell state plasticity contribute to homeostasis and disease, particularly therapy resistance in colorectal cancer. Her team has also pioneered organoid-based regenerative strategies, including the engineering of lab-grown human intestinal grafts from patient tissue, with potential applications in treating intestinal failure.