Investigating Craniofacial Development in Zebrafish

Credit: Kristin Ates
Using CRISPR genome editing in zebrafish, scientists with the Fralin Biomedical Research Institute at VTC linked an undiagnosed human disease with a rare genetic mutation that causes craniofacial abnormalities. The mutant zebrafish larva exhibited a striking increase in type II collagen, shown stained green in this underside view of lower jaw structures. Blue stain shows cell nuclei.
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