iPSC-Derived Cardiomyocyte

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Published: October 26, 2022

A stem cell-derived heart muscle cell. Proteins that are important for muscle cell contraction are highlighted in red and green, and cell nuclei are blue.

Credit: Joseph C Wu, MD, PhD/ Stanford Cardiovascular Institute

Researchers have created heart muscle cells called cardiomyocytes from induced pluripotent stem cells (iPSCs). These lab-made cardiomyocytes can then be used to test chemotherapy drugs for potentially heart-harming side effects. This image shows an iPSC-derived cardiomyocyte. Proteins that are important for muscle cell contraction are highlighted in red and green, and cell nuclei are blue.