Neuropathological Inclusions in the Brain

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Published: December 7, 2022

Mice expressing E46K alpha-synuclein developed neuropathological inclusions in the brain (shown in green) following injection with recombinant E46K fibrils. Red staining shows astrocytes, blue is cell nuclei.

Credit: Woerman Lab/ University of Massachusetts Amherst

This image was taken in relation to a study into a mutation in the misfolding protein that causes Parkinson’s disease, alpha-synuclein, and shows neuropathological inclusions in a mouse brain (in green), developed following injection with recombinant E46K fibrils. Red staining shows astrocytes, blue is cell nuclei.