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Patient-Derived Podocyte Kidney Cells
Editor's Pics

Patient-Derived Podocyte Kidney Cells

Patient-Derived Podocyte Kidney Cells
Editor's Pics

Patient-Derived Podocyte Kidney Cells

Credit: Dr Francesco Aulicino/ University of Bristol

This image of patient-derived podocyte kidney cells was taken in relation to a study into a DNA repair vehicle to genetically fix faulty podocin, a common genetic cause of inheritable Steroid Resistant Nephrotic Syndrome (SRNS).


Podocin is a protein essential for kidney function and is usually located on the surface of specialized kidney cells. Faulty podocin, however, terminally damages podocytes as it remains stuck inside the cell.


The image shows cells repaired with the novel approach, with podocin (green) on the cell surface.


Patient-Derived Podocyte Kidney Cells

Credit: Dr Francesco Aulicino/ University of Bristol


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