The diversity of potential mRNA-based therapies has led to increased interest in using synthetic mRNA as a tool in the treatment of multiple diseases. Nevertheless, obtaining larger quantities of synthetic mRNA for clinical treatment remains a challenge. Current mRNA production methods require multiple purification steps and various chemicals, thereby creating a bottleneck for large-scale manufacturing of in vitro transcribed (IVT) mRNA. To overcome these challenges, a new affinity chromatography resin for the isolation and purification of mRNA was developed.
- Simplify your mRNA downstream process
- Increase purity and yield
- Allow for scalable mRNA purification process without the use of toxic chemicals
