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APP NOTE

Rapid Mammalian Cell Harvest Without Centrifugation for Antibody Purification

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Monoclonal antibody expression systems typically utilise a signal peptide to ensure secretion of the antibody into the cell culture media. Although this reduces the complexity of purification and avoids the need for cell disruption, it does require the use of expensive and/or time-consuming techniques to separate cells from antibody-containing cell culture fluid.

Download this app note to discover a novel system that:

  • Enables rapid clarification of mammalian cell cultures without the need for centrifugation
  • Has no impact on product quality
  • Increases productivity and throughput clarification