An AAV is a non-enveloped virus with a lack of pathogenicity, low immunogenicity, broad tropism and persistent transgene expression in both proliferating and quiescent cells. This makes AAVs an attractive choice for creating viral vectors for gene therapy for a variety of diseases. AAV genome integrity analysis is a critical quality test, providing insights into transgene integrity and ensures product safety and efficacy.
Download this app note to discover a method that:
- Offers a quick assessment of AAV genome size purity with multiplex screening capability
- Provides excellent separation resolution from partial AAV genomes and small size impurities
- Is capable of analyzing the genome integrity of AAV samples of multiple serotypes or different genome sizes in one analysis
