Latest How To Guides

Cell heterogeneity is a key contributor to biological complexity that is often masked by bulk techniques, like RNA sequencing or microarray analysis.

Download this Guide to explore how NGS can benefit from the miniaturization and automation of library preparation workflows.

Download this guide to explore different water types and their uses, the implications of poor water quality and water storage.

The ability to visualize cells is crucial for all scientists hoping to understand cell behavior. This handbook will take you through common imaging protocols, critical notes, tips for running a successful experiment and the supplies needed for each.

Since the discovery of elevated levels of nitrosamines in certain pharmaceuticals, reported in July 2018, finding the right solutions have become a major focus for many pharmaceutical manufacturers, particularly as they are considered probable human carcinogens.

Messenger RNA (mRNA) therapy enables the body to make the proteins needed to prevent, treat or cure diseases but, unlike traditional biologics, mRNAs are large and delicate molecules that need to be protected by lipid nanoparticles (LNPs) on the journey to reach target cells.

This guide explores the critical role of ubiquitin in two protein degradation systems, the ubiquitin-proteasome system (UPS) and the autophagy–lysosomal system (ALS), in proteostasis.

Download this guide to learn about the barriers you’ll face on the road to creating the lab of the future and how you can start preparing today.

The journey to discovering novel drug targets starts with building a deep understanding of the underlying biology. To achieve this, researchers are increasingly looking to 3D cell cultures to bridge the gap between 2D cell cultures and in vivo animal models.

Download this guide to learn how you can improve your qPCR reagents, sample/template and quality control.