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Latest How To Guides

How To Prepare Protein Complexes for Mass Spectrometry: Success Is in the Details
How To Guide

The aim of this guide is to aid the experimental scientist in preparing samples for successful analysis by mass spectrometry and identification of the protein components of the complex.

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Are You in Control of Your Cells?
How To Guide

Designing controls for some experiments involving cells can be tricky, especially for beginners who do not realize how many factors are at play and must be controlled during cell culture.

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How To Choose the Right Western Blot Detection Method
How To Guide

It is important to understand the advantages and disadvantages of different ways of detecting a protein of interest on a western blot membrane. Here, we consider the three main types of protein detection for western blot; radioactive, enzymatic, and fluorescent.

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How To Create a shRNA Knockdown
How To Guide

An important RNAi-based method to silence a gene is through the delivery of artificial RNA molecules called short hairpin RNAs (shRNAs). This guide will focus on the design, delivery and use of shRNAs to create a long-term knockdown of a targeted gene.

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Immunohistochemistry: Tips and Techniques To Save Time, Money, and Tissue
How To Guide

Immunohistochemistry (IHC) is a technique that capitalizes on the specificity of the immune system to examine tissue stained to demonstrate the presence of certain proteins. In this guide, we have provided a sample IHC protocol followed by tips and techniques to optimize your IHC staining.

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Ultrapure Water for HPLC Analysis
How To Guide

Donwload this guide to explore how arium® pro VF can be used in HPLC to purify water.

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How To Successfully Implement a Laboratory Information Management System (LIMS)
How To Guide

This is the essential guide for any laboratory thinking of implementing a LIMS to improve processes and operational efficiency.

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Non-Targeted Environmental Sample Analysis: 4 Key Steps
How To Guide

This guide will take you through the key steps of collecting, transporting and preparing your samples ready for identifying contaminants by non-targeted analysis techniques.

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Optimizing Magnetic Bead Specificity and Binding Capacity
How To Guide

Download this guide to understand the basics of working with magnetic beads, their various applications and how to optimize bead specificity.

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A Guide to Measuring Drug-Target Residence Times with Biochemical Assays
How To Guide

This guide provides technical background on concepts and techniques for use of Transcreener® biochemical assays to measure drug-target residence times.

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