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Latest How To Guides

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How To Guide

An Introduction to Miniaturization in NGS Workflows

Download this Guide to explore how NGS can benefit from the miniaturization and automation of library preparation workflows.

A gloved hand holds a conical flask containing water. A glass pipette containing water can be seen to the left. In the background there are many test tubes.
How To Guide

Maintaining Water Quality in the Lab – Key Considerations

Download this guide to explore different water types and their uses, the implications of poor water quality and water storage.
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How To Guide

Nitrosamine Impurity Analysis Solutions Guide

Since the discovery of elevated levels of nitrosamines in certain pharmaceuticals, reported in July 2018, finding the right solutions have become a major focus for many pharmaceutical manufacturers, particularly as they are considered probable human carcinogens.
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How To Guide

Analytical Solutions for mRNA Vaccines and Therapeutics

Messenger RNA (mRNA) therapy enables the body to make the proteins needed to prevent, treat or cure diseases but, unlike traditional biologics, mRNAs are large and delicate molecules that need to be protected by lipid nanoparticles (LNPs) on the journey to reach target cells.
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How To Guide

Protein Degradation – A Guide to the Proteasome and Autophagy Systems

This guide explores the critical role of ubiquitin in two protein degradation systems, the ubiquitin-proteasome system (UPS) and the autophagy–lysosomal system (ALS), in proteostasis.
A smiling woman with short white hair, wearing a long-sleeved pink shirt stands in a lab, with her right arm raised and index finger touching a clear digital screen. In the background, three other out of focus people can be seen in the lab wearing white lab coats.
How To Guide

Preparing for the Lab of the Future

Download this guide to learn about the barriers you’ll face on the road to creating the lab of the future and how you can start preparing today.

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How To Guide

Seamless Science for 3D Cell Models

The journey to discovering novel drug targets starts with building a deep understanding of the underlying biology. To achieve this, researchers are increasingly looking to 3D cell cultures to bridge the gap between 2D cell cultures and in vivo animal models.
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How To Guide

Tips for Improving Your qPCR

Download this guide to learn how you can improve your qPCR reagents, sample/template and quality control.
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How To Guide

Cryogenically Storing Animal Cell Cultures

Maintaining the health of growing cell cultures is a demanding task made more difficult by the perpetual risk of loss through accidents or contamination. In addition, actively growing cell cultures are subject to age-related or environmentally-induced changes which can result in their ongoing evolution and potential loss.
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How To Guide

How To Build an Effective Protein Degrader

This guide highlights the four major stages of targeted protein degradation, the challenges at each step, and the questions you should ask yourself to ensure your final product will result in a complete protein degradation.
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