Supercharge Your Mass Spectrometry Workflow

• Low throughput SUPERCHARGE Your Mass Spectrometry Workflow and more! Liquid chromatography/mass spectrometry (LC/MS) empowers labs with the ability to separate, identify, and quantify a wide variety of compounds across numerous industries and application spaces. As adoption of this technology has grown, so has the demand for increased throughput and efficiency. By combining the sensitivity and specificity of mass spectrometry, automated sample handling, and innovative data acquisition techniques, high-throughput mass spectrometry (HTMS) overcomes common analytical bottlenecks. This infographic explores HTMS solutions that can allow you to unlock the potential of your lab. How RapidFire works Load/wash Binding solvent To waste To waste Elution solvent To waste Extra wash Wash solvent Elute To MS Re-equilibrate Binding solvent Analytes of interest Molecules similar to analytes of interest Salts Buffers RapidFire Cartridge RapidFire Cartridge RapidFire Cartridge RapidFire Cartridge RapidFire automates solid-phase extraction (SPE) and sample delivery from microplates to Agilent mass spectrometers. By replacing traditional liquid chromatography (LC) separation, data acquisition time is dramatically reduced to as little as 2 seconds per sample. How StreamSelect Works System 1 System 2 System 3 System 4 Collected MS Data 0 min 4 min 1 min 2 min 3 min StreamSelect orchestrates the connection of up to four chromatographic systems with a single mass spectrometer. By only collecting MS data during the elution stage of each chromatographic run, StreamSelect can stagger and overlap injections to quadruple throughput without any modification to the original LC/MS method. Common analytical bottlenecks • Low throughput • High cost per sample • Sample backlog • Laborious method development • Reduced workflow productivity HTMS enables labs to reduce data acquisition time to as little as seconds per sample. Agilent RapidFire and StreamSelect can accommodate unattended evening and weekend runs, stretching productivity further. These tools have become invaluable for labs requiring quick turnaround times and cost efficiency. Achieve more with HTMS • High throughput • Low cost per sample • Increase instrument efficiency • More time to focus on value-added tasks • Run samples with little-to-no operator intervention • Tight turnaround times Forensics Protein analysis Drug discovery Clinical research Toxicology Choose RapidFire 400 for the highest throughput capability • Integrated sample handling robotics • Support for 96-, 384-, and 1536-well plates; up to 138,240 samples • Ultrafast sample cleanup • Automated evening and weekend operation • Data acquisition time as short as 2 seconds • Hundreds of applications and publications of proven success Choose the StreamSelect LC/MS system for an optimized, integrated solution • Produce results up to four times faster • Maintain full chromatographic separation of samples • Easy-to-use • Fully integrated software • Online sample cleanup “I need to run thousands of samples per day” Agilent offers HTMS solutions with a variety of throughput and automation capabilities to suit your workflow needs. The right solution “I want to run hundreds of samples per day and differentiate isobaric compounds” Learn more about High-Throughput MS Systems, talk to an expert, or explore our Frequently Asked Questions Proven technology RapidFire 400 Barcode reader On-board plate storage Integrated microplatehandling robotics Temperature-controlled sample storage Automated cartridge exchanger Supports TQ, TOF, and QTOF StreamSelect Multi-column thermostat Optimal online sample cleanup Data quality without compromise Fully integrated software and hardware Temperature-controlled sample storage RA45037.4363888889