Cell culture has been advancing biological and biomedical research since the first cell line was established in the late 1940s. Cells have mostly been cultured in a two-dimensional (2D) format as a monolayer adhered to a dish or plate well. In the past two decades, however, researchers have begun to switch gears, transitioning away from 2D in favor of three-dimensional (3D) cultures.

Download this listicle to explore:

• Various 3D cell culture formats
• Key research areas that have harnessed 3D cultures