3D Cell Culture: Miniature Dimensions Drive Massive Advances

Listicle Dec 14, 2020 | By Masha G. Savelieff, PhD

Credit: Geoffrey Wahl, Christopher Dravis, National Cancer Institute/Salk Institute

Cell culture has been advancing biological and biomedical research since the first cell line was established in the late 1940s. Cells have mostly been cultured in a two-dimensional (2D) format as a monolayer adhered to a dish or plate well. In the past two decades, however, researchers have begun to switch gears, transitioning away from 2D in favor of three-dimensional (3D) cultures.

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Various 3D cell culture formats
Key research areas that have harnessed 3D cultures

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