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Cell Fusion "Awakens" Regenerative Potential of Human Retina
Hybrid cells that fuse adult stem cells with retinal cells have been shown to trigger the regenerative potential of retinal tissue, with the hybrid cells differentiating into cells similar to ganglion cells, which are essential for vision.
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A Potential Target for Anxiety-Reducing Drugs Discovered
Neuroscientists have identified a new target in the brain which underpins the eliciting of anxiety and fear behaviors such as "freezing".
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Measuring the Eye Could Reveal Brain Atrophy
Researchers have found a close connection between the dimensions of retinal structures and those of the brain. Their study results suggest that assessments of the eye’s retina could help to detect a loss of brain substance, i. e. “brain atrophy”.
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Priming the Tumor Environment To Improve Efficacy of Existing Therapeutics for Liver Cancer
Researchers have shown that by administering an immune checkpoint inhibitor to prime the tumor environment prior to a multikinase inhibitor, it's possible to boost the effectiveness of existing therapeutics for hepatocellular carcinoma.
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Trial of Three mRNA HIV Vaccines Launched
A Phase I clinical trial will explore the safety and immunogenicity of three preventive HIV vaccines using mRNA technology.
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mRNA Delivery of CRISPR-Cas 9 Tool To Improve Muscle Strength
Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.
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Ready, Set, Go! How Our Brain Plans Movement
Planned movement is essential to our daily lives, and it often requires delayed execution. As children, we stood crouched and ready but waited for the shout of “GO!” before sprinting from the starting line. Now, scientists have discovered the brain network that turns plans into action in response to this cue.
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Differences Detected in Immune Cell From Which Infant Leukemia Develops
A team has begun to unravel the mystery of why a particular form of leukemia in infants has defied efforts to improve outcomes, despite improvements being made for older children.
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Anyone Can Be Trained To Be Creative, Say Researchers
Researchers have developed a new method for training people to be creative, one that shows promise of succeeding far better than current ways of sparking innovation.
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An Image or the Real Thing? Mouse Brains Can Tell the Two Apart Inherently
Researchers have confirmed that mice perceive the inherent difference between a picture of an object and the actual 3D object itself.
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