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Priming the Tumor Environment To Improve Efficacy of Existing Therapeutics for Liver Cancer
Researchers have shown that by administering an immune checkpoint inhibitor to prime the tumor environment prior to a multikinase inhibitor, it's possible to boost the effectiveness of existing therapeutics for hepatocellular carcinoma.
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Trial of Three mRNA HIV Vaccines Launched
A Phase I clinical trial will explore the safety and immunogenicity of three preventive HIV vaccines using mRNA technology.
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mRNA Delivery of CRISPR-Cas 9 Tool To Improve Muscle Strength
Mutations that lead to muscle atrophy can be repaired with the gene editor CRISPR-Cas9. A team led by ECRC researcher Helena Escobar has now introduced the tool into human muscle stem cells for the first time using mRNA, thus discovering a method suitable for therapeutic applications.
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Ready, Set, Go! How Our Brain Plans Movement
Planned movement is essential to our daily lives, and it often requires delayed execution. As children, we stood crouched and ready but waited for the shout of “GO!” before sprinting from the starting line. Now, scientists have discovered the brain network that turns plans into action in response to this cue.
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Differences Detected in Immune Cell From Which Infant Leukemia Develops
A team has begun to unravel the mystery of why a particular form of leukemia in infants has defied efforts to improve outcomes, despite improvements being made for older children.
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Anyone Can Be Trained To Be Creative, Say Researchers
Researchers have developed a new method for training people to be creative, one that shows promise of succeeding far better than current ways of sparking innovation.
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An Image or the Real Thing? Mouse Brains Can Tell the Two Apart Inherently
Researchers have confirmed that mice perceive the inherent difference between a picture of an object and the actual 3D object itself.
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Cognitive Decline Is a Key Indicator of Lifespan in Alzheimer's Disease
According to a study, cognitive decline is the biggest factor in determining how long patients with Alzheimer’s disease will live after being diagnosed.
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Re-Engineering Red Blood Cells To Deliver Vaccines
Researchers have developed a new strategy for vaccine delivery by embedding the SARS-CoV-2 spike protein into red blood cell membranes.
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We May Have Microbes and Minerals To Thank for Earth’s Oxygenation-Rich Atmosphere
A new hypothesis suggests that oxygen finally started accumulating in Earth's atmosphere 2.3 billion years ago thanks to interactions between certain marine microbes and minerals in ocean sediments.
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