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Fat-Secreted Molecule Diminishes Effects of Common Cancer Drug content piece image
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Fat-Secreted Molecule Diminishes Effects of Common Cancer Drug

Leptin, a molecule produced by fat cells, appears to diminish the effects of tamoxifen, an estrogen-blocking therapy used to treat and prevent breast cancers.
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Study Raises Safety Concerns for Neuroblastoma Drug Candidate

A team from St. Jude Children’s Research Hospital has discovered the primary target of the experimental cancer drug CX-5164, revealing a possible risk for late effects of treatment.
Blood Tests Predict Which Prostate Cancer Patients Are Resistant to Chemotherapy Drug content piece image
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Blood Tests Predict Which Prostate Cancer Patients Are Resistant to Chemotherapy Drug

According to research, regular blood tests before and during chemotherapy for prostate cancer can detect whether or not a patient is resistant or developing resistance to treatment with docetaxel.
Lack of Important Molecule in Red Blood Cells Causes Vascular Damage in Type 2 Diabetes content piece image
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Lack of Important Molecule in Red Blood Cells Causes Vascular Damage in Type 2 Diabetes

Altered function of the red blood cells leads to vascular damage in type 2 diabetes. Results from a new study in cells from patients with type 2 diabetes and mice show that this effect is caused by low levels of an important molecule in the red blood cells.
Cellular Senescence Is Caused by Irreversible Damage to the Genome content piece image
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Cellular Senescence Is Caused by Irreversible Damage to the Genome

A team of researchers has shown for the first time that cellular senescence is caused by irreversible damage to the genome rather than simply by telomere erosion.
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Multiplex Network Improves Diagnosis and Analysis of Rare Diseases

The network will help understand underlying mechanisms of rare diseases and thus enables identification of causative genetic defects more accurately.
A Key Aspect of Mindfulness Theory Is Being Misunderstood content piece image
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A Key Aspect of Mindfulness Theory Is Being Misunderstood

Research has found that mindful awareness is about both accepting and engaging with life’s challenges, and that’s what popularized concepts of mindfulness tend to miss.
The Placebo Effect (and Dopamine) Can Affect Antidepressants' Efficacy content piece image
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The Placebo Effect (and Dopamine) Can Affect Antidepressants' Efficacy

Levels of dopamine and the placebo effect can determine whether patients with social anxieties improve when treated with SSRIs. A new study shows the effect was four times higher for patients with high expectations of the medication compared with patients with low expectations.
Nitrous Oxide Emissions From Agricultural Soils Should Be Factored Into Climate Change Mitigation Efforts content piece image
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Nitrous Oxide Emissions From Agricultural Soils Should Be Factored Into Climate Change Mitigation Efforts

Poorly drained agricultural soils emit enough of the greenhouse gas nitrous oxide that the resulting climate change effects could far exceed the benefits of using the same soils as a means of sequestering carbon, according to a recently published scientific study.
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Genomic Tools Boost Rice Breeding

Rice traits are hugely important predictors of rice sales and consumption. It can be expensive and time-consuming to refine these traits and breeders have other important traits to think about. New research allows Latin American rice breeders to select regionally relevant eating-quality traits from the outset of a breeding program, saving time, effort and money.
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