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State-of-the-Art Imaging Reveals Live Deep Brain Neurons in Unprecedented Detail
A pioneering technique developed by the Prevedel Group at EMBL allows neuroscientists to observe live neurons deep inside the brain – or any other cell hidden within an opaque tissue.
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Which Protein Best Predicts Alzheimer's Effects on Memory?
Researchers have compared how well different Alzheimer’s biomarkers predict the progression of the disease and its effect on the memory. They found that early accumulation of tau proteins in the brain as measured by PET scanner was more effective at predicting memory impairment than biomarkers in the cerebrospinal fluid or amyloid plaque in the brain.
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Copper Cysteamine Inhibits the Proliferation of Deep-Seated Tumors
Two new papers explore the effects of copper cysteamine, a next-generation cancer photodrug, as a means to reduce radioactive doses and side effects when treating deep-seated tumor cells.
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Brain-Pruning Protein Discovery May Help Epilepsy Treatments
Researchers at the University of Bonn have shed light on the function of the enzyme SLK for the development of nerve cells in the brain, a discovery that may produce enhanced treatments for epilepsy.
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Biomarkers of Pain Could Lead to Better Therapies
Researchers have mapped the biomarkers of different types of pain to categorise and better treat them in the future.
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Manic Episodes in Bipolar Disorder Linked to Brain Thinning
Patients with bipolar disorder who experience manic episodes are more likely to show abnormal brain changes over time, according to one of the largest longitudinal brain imaging studies in its field to date. The study, led by researchers at Karolinska Institutet and University of Gothenburg in Sweden, also confirms links between bipolar disorder and accelerated brain ventricle enlargement
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Linker Histones Tune the Length and Shape of Chromosomes
New research has identified proteins called linker histones as the factor that controls whether DNA winds into long and thin chromosomes, made up of many small loops, or short and thick chromosomes with fewer large loops.
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Past Suffering Affects How We Give Praise
A team of researchers from the University of Missouri have discovered that people tend to give more praise to someone for their good deeds as an adult after discovering that person has also had to overcome adversity or suffering earlier in life, such as abuse and neglect as a child.
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Exploring the Dance of Key Proteins Behind Circadian Rhythms
Using the relatively simple clocks found in fruit flies (Drosophila melanogaster), researchers reveal that the subcellular location of clock proteins and genes fluctuates with the daily passage of time, indicating that spatial information is translated into time-related signals.
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Genetic Mutation in Mice and Monkeys Interferes With HIV and Ebola
A nationwide team of researchers has determined how a genetic mutation found in mice and monkeys interferes with viruses such as HIV and Ebola. They say the finding could eventually lead to the development of medical interventions in humans
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