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Antibody-Producing B Cells May Have Predetermined Fates
A protein called Oct2 has been identified as the master regulator behind the development of antibody-producing cells. The findings may help understand how certain cancers arise.
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Online Tool Helps Residents Reduce Traffic-Related Air Pollution Impact
Researchers have released a new online tool to help schools, hospitals and residents understand and reduce the impact of traffic-related air pollution.
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Estrogen Receptor Provides Clues To Overcome Resistance to Anticancer Drugs
Estrogen receptor α (ERα) plays a key role in several breast cancers. New research in Cell reports that in addition to its activity in the nucleus, it can also help cancer cells overcome anticancer mechanisms and develop resistance to treatment.
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No Association Between Nuts and Weight Gain
Researchers have found that nuts do not contribute to weight gain. It provides further evidence that long-standing concerns about nuts and weight gain – often found in popular media and clinical nutrition guidelines – are unwarranted.
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AI Identifies New Drug Combo for Aggressive Childhood Brain Cancer
Scientists have used tools enhanced with AI to successfully propose a new combination of drugs for use against an incurable childhood brain cancer.
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Small Molecule Reduces Neuroinflammation in Preclinical Study
In a preclinical study published in Glia, researchers report that the small molecule drug SRI-42127 can potently reduce the triggers of neuroinflammation.
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Fossilized Footprints Provide Earliest Evidence of Humans in the Americas
Footprints found at White Sands National Park in New Mexico provide the earliest unequivocal evidence of human activity in the Americas and offer insight into life over 23,000 years ago.
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More Than 80% of Cancer Therapies in Phase 3 Trials Fail To Meet Overall Survival Goals
Research has found that more than 80% of therapies tested in Phase III oncology trials did not achieve meaningful clinical benefit in prolonging survival.
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Dementia Symptoms' Appearance Can Be Estimated Via Brain Scan
Researchers at Washington University School of Medicine in St. Louis have developed an approach to estimating when a person who is likely to develop Alzheimer’s disease, but has no cognitive symptoms, will start showing signs of Alzheimer’s dementia.
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MIND Diet Foods Associated With Better Cognitive Performance
Aging takes a toll on the body and on the mind. For example, the tissue of aging human brains sometimes develops abnormal clumps of proteins that are the hallmark of Alzheimer’s disease. How can you protect your brain from these effects? Researchers have found that older adults may benefit from a specific diet even when they develop these protein deposits.
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