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Identifying Chemicals That Activate Fat-Forming Pathways
Researchers have used machine learning methods to characterize chemicals in furniture, plastic housewares and pesticides that activate fat-forming pathways.
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Identifying Metabolism-Disrupting Chemicals With Machine Learning
Chemicals in your furniture, plastic housewares and pesticides used in your yard may be making you fat, according to Boston University Schools of Medicine (BUSM) and Public Health (BUSPH) researchers.
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Masitinib Inhibits the Replication of SARS-CoV-2 in Preclinical Models
Scientists have discovered that the drug masitinib may be effective in treating COVID-19. They also found that it could be effective against other types of coronaviruses, in addition to SARS-CoV-2, as well as picornaviruses.
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Common Insecticide Is Harmful to Bees in Any Amount
A study shows that neonicotinoids, a type of insecticide made for commercial plant nurseries, are harmful to a typical bee even when applied well below the label rate.
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Mini Brain Models Used To Study Alzheimer’s and Test Drugs
Researchers have developed a powerful miniature brain platform to study the mechanistic causes of Alzheimer’s disease and to test dementia drugs in development.
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15 Novel Biomarkers Linked to Late-Onset Dementias
A study by an international research group identified 15 novel biomarkers that are linked to late-onset dementias. These biomarkers are proteins, which predict cognitive decline and subsequent increased risk of dementia already 20 years before the disease onset.
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Cancer Vaccine Efficacy Assessed Using Lynch Syndrome Model
A novel strategy for developing vaccines against cancer has shown promise in a proof-of-concept study. The preclinical results could eventually lead to vaccines that cause the immune system to target cancers early in their development, preventing the disease from becoming established.
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Researchers Investigate How Two Key Anticancer Drugs Work
Scientists have published findings of their research into how two important antibody drugs, rituximab and obinutuzumab, work and why they are sometimes ineffective in subsets of patients.
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Cryptic Transcription in Mammalian Stem Cells Linked to Aging
Although visible signs of aging are usually unmistakable, unraveling what triggers them has been quite a challenge. Researchers have discovered that a cellular phenomenon called cryptic transcription, which had been previously described and linked to aging in yeasts and worms, is elevated in aging mammalian stem cells.
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Key Stem Cell Dormancy Mechanism Discovered
Princess Margaret Cancer Centre researchers have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number of cancers.
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