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Bacterial Traffic Jams Linked to Antibiotic Resistance Development
The bacterial equivalent of a traffic jam causes multilayered biofilms to form in the presence of antibiotics, shows a recent study. This collective behavior may contribute to the emergence of antibiotic resistance. These insights could pave the way to new approaches for treating bacterial infections that help thwart the emergence of resistance.
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Novel Mechanism Underlying Hair Thinning Identified
Hair grows from stem cells residing in hair follicles and during aging, the follicles lose the capability to grow hair, leading to hair thinning and ultimately hair loss. In a new study, researchers have identified a novel mechanism by which hair follicles lose their regenerative capabilities.
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Fat Production Doubled by Sugar Consumption
Too much sugar is unhealthy – that we know, but it’s not just down to the many calories. Even moderate amounts of added fructose and sucrose double the body’s own fat production in the liver, researchers have shown. In the long term, this contributes to the development of diabetes or a fatty liver.
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Could Industrial Pollution Exposure Be Contributing to Increase in Cryptorchidism?
According to a study, environmental pollution from industries such as coal mining and metal works may play a role in the increasing numbers of boys born with undescended testicles.
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Stem Cells Derived From Fat Show Promise as a Treatment for Mass Radiation Exposure
Researchers have demonstrated, for the first time, how allogeneic adipose-derived stem cells can mitigate total body irradiation-induced acute radiation syndrome.
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How SARS-CoV-2 Mutations Enables Immune Evasion Revealed
A new study offers a look into the ways in which compromised immunity may render SARS-CoV-2 fitter and capable of evading the immune system. The research shows that a mutated SARS-CoV-2 from a chronically infected immunocompromised patient is capable of evading both naturally occurring antibodies from COVID-19 survivors as well as lab-made antibodies now in clinical use for the treatment of COVID-19.
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Finding New Uses for Existing Drugs
Researchers have uncovered potential novel therapeutic strategies for oral and esophageal carcinomas. The researchers found that combining two drugs, pitavastatin and capmatinib, inhibited the viability of oral cancer cells in culture, as well as the growth of tumors in a mouse model.
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A Potential Target for Anti-COVID-19 Therapies
Researchers have identified a potential new target for anti-COVID-19 therapies, a coronavirus enzyme called PLpro (papain-like protease).
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Crying Human Tear Glands Grown in the Lab
Researchers have used organoid technology to grow miniature human tear glands that actually cry. The organoids serve as a model to study how certain cells in the human tear gland produce tears or fail to do so.
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Whole Genome Sequencing Enables More Precise Diagnoses for Patients With Rare Diseases
More than 1,200 people with rare diseases have received a diagnosis thanks to the integration of large-scale genomics into the Stockholm region's healthcare system.
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