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Team Discovers a Detonating Fuse for Basal-Like Breast Cancer
Basal-like breast cancer requires the support of the YAP protein to stimulate the growth of cancer stem cells. Targeting YAP could be a potential treatment strategy against this type of cancer in the future.
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Low-Cost Pinprick Test Measures COVID-19 Immunity in Under One Hour
The new method is called SATiN, which stands for Serological Assay based on split Tripart Nanoluciferase. It is the first COVID-19 serology test that uses highly sensitive protein complementation chemistry in which a light-emitting luciferase protein is reconstituted from separate fragments as test readout.
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Ibuprofen Disrupts Key Protein Complex in Colorectal Cancer Cells
The mechanism behind the anti-tumor properties of NSAIDs has been largely attributed to the inhibition of cyclooxygenases, however, several studies have shown that the chemopreventive properties of ibuprofen also involve multiple COX-independent effects.
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Anti-Androgen Drugs May Disarm COVID-19 Spike Protein
Finding from a preclinical study suggest that anti-androgen therapies may help to disarm the coronavirus spike protein used to infect cells, by reducing androgen levels. Two receptors, ACE2 and TMPRSS2, are regulated by androgen and facilitate SARS-CoV-2's entry into host cells.
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Cellular Fingertips May Help Cells "Speak" to Each Other
What if you found out that you could heal using only a finger? It sounds like science fiction, reminiscent of the 1982 movie E.T. Well, it turns out that your body's own cells can do something similarly unexpected.
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Behavioral Effects of Alcohol May Be Caused by Breakdown Products Produced in the Brain
Researchers have demonstrated that alcohol metabolism can occur in the mouse brain, due to the presence of the enzyme aldehyde dehydrogenase 2 (ALDH2). They also demonstrated that expression of ALDH2 in the mouse cerebellum mediates behavioral effects related to alcohol intoxication. The paper was published in Nature Metabolism.
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Study Shows Baboons, Like Humans, Can Solve Abstract Reasoning Tasks
A new study has suggested that baboons can solve abstract reasoning problems using cognitive tools previously thought to be solely the reserve of humans.
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Virtual Reality Could Reduce Pain for People With Nerve Injuries
People with nerve injuries often have a dysfunctional pain suppression system, making them particularly prone to discomfort. Researchers have uncovered that virtual reality (VR) can reduce types of pain typically seen in patients with nerve injuries - and that VR can boost the dysfunctional pain suppression system.
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Reprogramed Cells Repair Brain Tissue Damage After Stroke
Many stroke victims don't receive treatment fast enough to prevent brain damage. Scientists have developed technology to "retrain" cells to help repair damaged brain tissue. It's an advancement that could help patients regain speech, cognition and motor function in the future.
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Step Forward in Identifying Plutonium Pollution
Researchers looking at miniscule levels of plutonium pollution in our soils have made a breakthrough which could help inform future "clean up" operations on land around nuclear power plants, saving time and money.
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