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Epigenetic Biomarker in Father’s Sperm Linked to Autism
In a study published in the journal Clinical Epigenetics, researchers identified a set of genomic features, called DNA methylation regions, in sperm samples from men who were known to have autistic children.
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This Is How Gene Mutations Lead to Kabuki Syndrome
Scientists have known for years that mutations in the MLL4 gene can cause Kabuki syndrome, a rare developmental disorder. But a new study illuminates new details regarding how this occurs.
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Tea and Coffee Get a Probiotic Twist
Good news for those who need a cuppa to start the day. Food scientists have created new probiotic coffee and tea drinks that are packed with over 1 billion units of gut-friendly live probiotics. Unlike traditional probiotics, they are non-dairy, plant-based beverages and can be stored at room temperature for more than 14 weeks.
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The Brain Encodes the "Where" and "When" of Memory Separately
A new study sheds light on how the timing of a memory is encoded in the hippocampus, and suggests that time and space are encoded separately.
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Study Finds Shortened Telomeres in Patients With Severe COVID-19
Patients with severe COVID-19 disease have significantly shorter telomeres, according to a study conducted by researchers at the Spanish National Cancer Research Centre (CNIO) in collaboration with the COVID-IFEMA Field Hospital, published in the journal Aging.
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Trace Chemicals Can Be Detected With Chemical Sensing Chip
Researchers have reported an advancement of a chemical sensing chip that could lead to handheld devices that detect trace chemicals — everything from illicit drugs to pollution — as quickly as a breathalyzer identifies alcohol.
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Surprising Behavior of T Cells Could Explain Some Bone Loss
In diseases characterized by bone loss—such as periodontitis, rheumatoid arthritis, and osteoporosis—there is a lot that scientists still don’t understand. But a recent study describes unexpected behavior of T cells that unlocks a piece of the puzzle.
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Big Data Analysis Pinpoints Cancer’s Key Vulnerabilities
Thousands of genetic mutations have been implicated in cancer, but a new study analyzing ~ 10,000 patients discovered that regardless of the cancer's origin, tumors could be stratified in only 112 subtypes. Within each tumor subtype, the Master Regulator proteins that control the cancer's transcriptional state were almost identical.
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Inhibiting Glutamine Metabolism Could Be an Effective Therapeutic Strategy for ARID1A-Mutant Ovarian Cancer
According to a new study, mutations that inactivate the ARID1A gene in ovarian cancer increase utilization of the glutamine amino acid making cancer cells dependent on glutamine metabolism. The researchers also demonstrated that pharmacologic inhibition of glutamine metabolism could be an effective strategy for treating ARID1A-mutant ovarian cancer.
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New Approach to CAR T-Cell Therapy Developed To Fight Lymphomas
Researchers have developed a novel approach to CAR T-cell therapy. The team has shown, using tumor cells and mouse models, that the therapy is very effective, especially when it comes to treating follicular lymphomas and chronic lymphocytic leukemia
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