News

New research has uncovered the presence of CD19 -- a B cell molecule targeted by chimeric antigen receptor (CAR) T cell immunotherapy to treat leukemia, lymphoma, and multiple myeloma -- in brain cells that protect the blood brain barrier (BBB).

A new study compares the immune responses of adults and children with COVID-19. The study findings detected key differences that may contribute to understanding why children usually have milder disease than adults.

A new study led by Boston Medical Center researchers indicates a well-known biomarker that serves as a marker for earlier diagnosis of neurodegenerative diseases is now detectable in the eye.

Researchers report novel findings concerning the therapeutic mechanisms of pomalidomide. They showed that pomalidomide causes the breakdown of a protein called ARID2. ARID2 promotes the "expression" of genes that are critical for the growth of multiple myeloma cells, so breaking down ARID2 is harmful to the cancer cells and beneficial to patients.

A new study has laid out the steps that connect the neuromuscular disorder spinal muscular atrophy (SMA) to the mutations in the gene SMN1 that cause the condition. The research may explain how the mutations affect motor neurons and points the way to a better understanding of SMA.

In a Phase I clinical trial for patients with advanced solid cancers marked by KRAS G12C mutations, the KRASG12C inhibitor sotorasib (AMG 510) resulted in manageable toxicities and durable clinical benefit.

A new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers identified high levels of a specific receptor in immune cells, giving promising evidence of a single cause for the disease.

Researchers at EPFL have developed remote-controlled, mechanical microdevices that, when inserted into human tissue, can manipulate the fluid that surrounds them, collect cells or release drugs. This breakthrough offers numerous potential applications in the biomedical field, from diagnostics to therapy.

Scientists have identified a new drug that could prevent or mitigate the consequences derived from SARS-CoV-2 infection.

Every day, we make hundreds of decisions. Decisions like these are shaped by our own values and preferences but understanding how our brains make these choices is still not well understood. Now, a new study has identified a new area of the brain that could be involved in cost-benefit decision-making.