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Tiny Antibody Component Neutralizes SARS-CoV-2 in Animal Models
Scientists have isolated the smallest biological molecule to date that completely and specifically neutralizes SARS-CoV-2. This antibody component, which is 10 times smaller than a full-sized antibody, has been used to construct a drug, called Ab8, which holds potential as a therapeutic and prophylactic against SARS-CoV-2.
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Collaborations Aim To Meet Unmet Clinical Needs in Biomarker Discovery and Characterization
Thermo Fisher Scientific announced agreements with AstraZeneca and the University of Nebraska Medical Center that will showcase new workflows to improve the throughput, robustness and standardization of clinical biomarker analysis.
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COVID-19 Phase 3 Trial To Evaluate REGN-COV2 Antibody Cocktail in UK
RECOVERY (Randomised Evaluation of COVid-19 thERapY), one of the world’s largest randomized clinical trials of potential COVID-19 treatments, will evaluate Regeneron’s investigational anti-viral antibody cocktail known as REGN-COV2. The Phase 3 open-label trial in patients hospitalized with COVID-19 will compare the effects of adding REGN-COV2 to the usual standard-of-care versus standard-of-care on its own.
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Stem Cell Research Uncovers Treatments for Genetic Parkinson's
In a seven-year research effort, an international team of scientists has clarified the cause for certain genetic forms of Parkinson's disease, and has identified potential pharmacological treatments.
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"Molecular Bridge" Restores Lost Connections in the Mouse Spinal Cord and Brain
A molecule created by researchers can restore lost connections in the spinal cord and brain of mice with neurological disorders including cerebellar ataxia, Alzheimer's disease and spinal cord injury. The research describes how the molecule repaired function in cells and in mouse models of diseases and injury.
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Massive-Scale Genomic Study Explores Diversity and Desirable Traits in Wheat
A scientific team including James Hutton Institute researchers has completed one of the largest genetic analysis ever done of any agricultural crop to find desirable traits in wheat’s extensive and unexplored diversity.
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Anxiety and Depression Linked to Lower Bone Density
Clinical studies have found that bone mineral density in patients with anxiety or depression is lower than in other people.
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COVID-19 Patients Put on Ventilators Can Develop Permanent Nerve Damage
Severely ill COVID-19 patients on ventilators are placed in a prone (face down) position because it’s easier for them to breathe and reduces mortality. But that life-saving position can also cause permanent nerve damage in these vulnerable patients, reports a new study.
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GWAS Pinpoints Gene Linked to Decreased Alcohol Cirrhosis Risk
Researchers at Indiana University School of Medicine are learning more about how a person’s genes play a role in the possibility they’ll suffer from alcoholic cirrhosis with the discovery of a gene that could make the disease less likely.
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Compound Blocks Key Enzyme Involved in Development of Muscular Dystrophy
Researchers at Yale have identified a possible treatment for Duchenne muscular dystrophy, a rare genetic disease for which there is currently no cure or treatment. The team discovered a compound that was able to target, and bind to, an enzyme that had previously been considered “undruggable.”
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