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Type 2 Diabetes Drugs Work Better Tethered Together
Biomedical engineers have shown that the efficacy of a two-pronged Type 2 diabetes treatment is improved when the drugs are linked by a heat-sensitive tether rather than being concurrently administered.
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Toxic Lead Measured in Minutes
Researchers have created a miniature device for measuring trace levels of toxic lead within minutes – far faster than currently available laboratory-based tests.
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Synthetic Coating for GI Tract Could Aid Drug Delivery
In a study conducted in pigs, researchers have demonstrated that by applying a temporary synthetic coating to the lining of the small intestine, it was possible to simplify the delivery of drugs that normally have to be taken multiple times per day.
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Detecting Pancreatic Cancer at Treatable Stages
Researchers at the University of Missouri’s College of Veterinary Medicine and School of Medicine have identified novel pieces of biological information, such as RNA, which may serve as biomarkers for early detection of pancreatic cancer.
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Deep Learning Algorithm Could Remove Materials Discovery Bottleneck
Researchers have developed a deep learning-based smart algorithm that has the potential to greatly speed up the discovery of novel functional materials.
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Mapping the Brain Circuits Behind Mania
Identifying the brain circuits affected in these "lesional" cases of mania, in addition to contributing to understanding the underlying mechanisms, could help find more effective treatments for bipolar disorder. A team of scientists from Portugal and the USA have now announced significant progress in the matter.
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In a World First, Researchers Reversibly Block Primate Brain Pathway
For the first time ever, neurophysiologists have succeeded in reversibly disabling a connection between two areas in the brains of primates while they were performing cognitive tasks.
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Antagonistic Genes Help Regulate Rice Plant Stem Growth
Scientists at Nagoya University and colleagues in Japan have identified two antagonistic genes involved in rice plant stem growth.
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LocoMouse Could Help Researchers Study How Brain Diseases Are Linked to Walking Deficits
Until recently, scientists did not have tools to systematically characterise specific walking deficits in different mouse models of neurological conditions. To solve this problem, Megan Carey's lab, at the Champalimaud Centre for the Unknown in Portugal, developed LocoMouse: an automated movement-tracking system that captures the fine details of locomotion in mice.
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How RNA Quality Control Fails in ALS
A fault in the RNA quality control system of cells leads to the haywire production of toxic proteins in ALS, according to a new study.
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