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TAF15 Protein Found in the Brains of Early-Onset Dementia Patients

Scientists have identified abnormal aggregates of a protein called TAF15 in the brains of individuals with early-onset dementia, known as frontotemporal dementia, where the cause was not previously known.
A 3D printed stencil of DECTIN-1's structure.
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Fungus-Fighting Protein Also Exacerbates Autoimmune Diseases

A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases.
A person holding a pill in the palm of their hand.
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Arthritis Drug May Offer Hope for Type 1 Diabetes

A common drug used for rheumatoid arthritis – baricitinib – has shown promising results for patients with type 1 diabetes in a world-first trial, showing it could limit the progression of the disease within the first 100 days of diagnosis.
Pouring espresso shot.
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Coffee Ground With Water Makes for a More Intense Espresso

Grinding coffee generates static electricity, which causes the coffee particles to clump and stick to the grinder. But does this clumping affect the taste of coffee? Yes, but water can make things slick again.
neurons covered in cobwebs.
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Five Early Warning Signs of Multiple Sclerosis

Researchers show that, on a population scale, the frequency of disorders such as depression, constipation, and urinary tract infections is associated with a diagnosis of multiple sclerosis five years later.
Pancreas highlighted in red.
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Stimulating Vagal Nerves Connected to the Pancreas Regenerates Insulin-Producing Cells

In a promising development, a research group has revealed that stimulating autonomic vagal nerves connected to the pancreas can improve the function and also increase the number of pancreatic β-cells in mice.
A human anatomy model with the brain showing.
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Brain Stimulation May Improve Memory Ability in Individuals With Schizophrenia

Most people with schizophrenia have extensive impairment of memory, including prospective memory, which is the ability to remember to perform future activities.
T cells.
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Why Do Our Immune Cells Need an Influx of Water and Salts To Move?

Researchers have shown that an influx of water and ions into immune cells allows them to migrate to where they’re needed in the body.
A sample of lab-grown psychedelic mushrooms.
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Magic Mushroom Genomes Reveal Route to “Designer” Fungi

A community-led study has revealed a trove of genomic data for over 100 cultivars of “magic” mushrooms. The research details how domestication has reduced the genetic diversity of the mushroom.
A model of a human brain with colored string emitting from the sides.
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Neuronal "Spike" Analysis Reveals How Memories Are Formed

The simple activity of walking through a room jumpstarts the neurons in the human brain. Researchers have long thought that spike rates are connected to behaviour and memory.
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