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How Cell Diversity Emerges
A research team at the Max Planck Institute for Molecular Genetics in Berlin has explored the role of factors in embryonic development that do not alter the sequence of DNA, but only epigenetically modify its “packaging”. They describe how regulatory mechanisms contribute to the formation of different tissues and organs in early mouse embryos.
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Team Develops Synthetic Blood-Thinner With No Bleeding Side Effects
Scientists have developed a highly selective and highly stable synthetic blood-thinning molecule that, unlike others, doesn’t cause bleeding adverse effects.
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Blood Test Could Diagnose Baby Brain Damage Just Hours After Birth
A newly developed blood test could detect which babies deprived of oxygen at birth are at risk of serious neurodisabilities like cerebral palsy and epilepsy.
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NIH Announces Clinical Trial To Test Monoclonal Antibodies for COVID-19
A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.
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RLF-100 Trial Shows Rapid Recovery From Respiratory Failure in Critically Ill Patients With COVID-19
A clinical trial of RLF-100 (aviptadil) has shown rapid recovery from respiratory failure in critically ill patients with COVID-19.
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Bone Cancer Discovered in Dinosaur From 77 Million Years Ago
Researchers have reported the discovery and diagnosis of a type of aggressive malignant bone cancer, called osteosarcoma, for the first time ever in a dinosaur.
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Inbreeding Detrimental for Survival in Birds
Biologists have long known that inbreeding can be detrimental. Inbreeding results in less genetic variation, making species more vulnerable if changes occur that require them to adapt. Now we know more about just how bad inbreeding really is.
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FMR1 Premutation Carriers Show Brain Connectivity Reductions
A new paper reveals a possible early indicator of Fragile X-associated tremor/ataxia syndrome, or FXTAS. The disease afflicts some older people who carry a "premutation" of the gene known as FMR1, which can lead to impairments in movement and cognition -- while other people who carry the premutation are unaffected.
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Circulating DNA From Tumor Could Predict Immunotherapy Outcome
A newly developed test that detects changing levels of tumor fragments in the blood may be an easy, non-invasive and quick way to predict who will benefit from immunotherapy, according to researchers.
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Gene Variants Help Explain Why People of African Descent Have Far Higher Stroke Risk
African-Americans have up to three times the risk of dying from strokes as people of European descent, yet there has been little investigation of if and how genetic variants contribute to their elevated stroke risk. Until now.
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