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New Insights Into the Impact of Stochasticity in Gene Expression
Researchers have uncovered new insights into the impact of stochasticity in gene expression, offering new evolutionary clues into organismal design principles in the face of physical constraints.
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Switching Immune Cells From “Protect” to “Attack” Mode To Treat Prostate Cancer
Researchers found that immune cells called macrophages, which are typically found in prostate cancer tumors to help promote growth, can be rewired to attack the disease using therapeutics.
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The Influence of "Future Foods" on Meat Quality Investigated
The cultivation of insects and microalgae are up-and-coming sectors to meet protein demands for humans and animals alike. A research team investigated whether these alternative protein sources alter typical meat quality.
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Chemo-induced Changes in Tumors Trigger Blood Vessel Anomalies
Scientists have identified how inflammatory alterations in tumors caused by chemotherapy treatment trigger blood vessel anomalies and thus drug-resistance, resulting in poor prognosis of cancer patients.
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Unprecedented Details of Tooth Enamel Structure Revealed
Scientists used a combination of advanced microscopy and chemical detection techniques to uncover the structural makeup of human tooth enamel at unprecedented atomic resolution.
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Novel Pathology Could Improve Diagnosis and Treatment of Huntington’s Disease
Researchers have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington’s disease, and could be used to improve their diagnosis and treatment.
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Next-generation Sequencing To Provide Precision Medicine for Rare Metabolic Disorders
Scientists have uncovered the genetic basis of aromatase deficiency – a rare metabolic disorder – using next-generation sequencing, paving the way towards precision medicine.
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Testing Patients for Endothelial Cell Injury Could Help To Predict COVID-19 Severity
Researchers at Yale have found that injury to endothelial cells may be a key driver of COVID-19 severity and death. The discovery suggests that doctors could both test patients for endothelial cell injury, known as endotheliopathy, and mitigate it with drugs to improve patient outcomes.
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SARS-CoV-2 Can Infect Heart Cells in a Lab Dish
A new study shows that SARS-CoV-2, the virus that causes COVID-19, can infect heart cells in a lab dish, indicating it may be possible for heart cells in COVID-19 patients to be directly infected by the virus.
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Findings From "Mini-brain" Study Suggest SARS-CoV-2 Can Infect Human Brain Cells
A multidisciplinary team from two Johns Hopkins University institutions has found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.
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