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The binding of the leukemia-associated NPM1c protein to the recycling regulator GABARAP.
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Leukemia Cells Activate Cellular Recycling Program

Around one-third of patients with acute myeloid leukemia (AML) have a mutation that affects the NPM1 gene. According to research, the altered protein produced by this mutation intervenes in autophagy and enables leukemia cells to speed up their growth.
Plastic straws breaking into smaller and smaller pieces.
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Snail-Inspired Robot Could Scoop Up Ocean Microplastics

The Hawaiian apple snail has inspired the design of a robot prototype that may one day scoop up ocean microplastics.
A smart watch worn on a person's left wrist.
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Limestone Putty Nanogenerator Harvests Energy From Everyday Motion

Triboelectric nanogenerators (TENGs) are small devices that convert mechanical or thermal energy into electricity for use in small, wireless autonomous devices. Researchers have now created a more cost-effective TENG that is simpler to build.
Tuberculosis-causing bacteria.
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Drug-Resistant Tuberculosis May Be Under-Diagnosed

A proportion of patients with drug-resistant tuberculosis (TB) receive ineffective treatment due to misdiagnosis by rapid molecular tests, reports a genomic analysis from Mozambique.
A closeup photo of someone's ear.
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People With Tinnitus May Have Nerve Loss in Their Ears

A new study shows people with tinnitus may have nerve loss in their ears that is not detected by conventional hearing tests.
An old woman wearing glasses and dressed in black sits facing to the right.
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How Prion Proteins Can Trigger Dementia

Dysfunction of the TDP-43 protein is associated with amyotrophic lateral sclerosis and frontotemporal dementia. Researchers have now shown that misfolded prion proteins can inactivate TDP-43.
Pink pills in a blister pack.
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Discovery Could Enhance Liver Cancer Drug’s Effectiveness

A breakthrough in the understanding of the relationship between a naturally occurring enzyme and the liver cancer drug sorafenib could improve the effectiveness of the drug.
An older man sits using a laptop surrounded by plants.
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Daydreaming Is More Pleasant in Old Age

According to a study, our minds wander less as we age and, when older adults do let their minds drift, they’re more likely to be distracted by pleasant thoughts rather than worries.
Histological slide (H & E stain at x300) showing prostate cancer.
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Why Do Some Prostate Cancers Become Resistant to Hormone Therapy?

Two new studies led by researchers from the UCLA Jonsson Comprehensive Cancer Center give insight into how cells use energy to influence the way prostate tumors survive and grow.
White pills on a light blue surface.
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Study Examines Effect of Aspirin on Cancer Treatment

Aspirin is inexpensive and readily available in almost every country. According to a meta-analysis, taking a daily low dose (75 or 81 mg/day) of aspirin was associated with a 20% reduction in deaths from cancer and in deaths from all causes.
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