News

A small-molecule inhibitor of the metabolic enzyme glutaminase (GLS1), is under investigation in a Phase I trial for certain patients with lung and ovarian cancers.

Experts review potential clinical approaches from antivirals to gene therapy against SARS-CoV-2, the coronavirus responsible for COVID-19 and related diseases.

A new approach to monitoring SARS-CoV-2, known as wastewater-based epidemiology, mines sewage samples for vital clues about human health. It can potentially identify levels of coronavirus infection at both a local and global scale.

It is well-known that a group of our ancestors left Africa and, about 50,000 years ago, met Neanderthals in Europe, and then had children with them. A new analysis shows that the Neanderthals may have had children with another extinct species of human (Denisovans), before they met Homo Sapiens, and that these children have been fertile and transferred genes from both species further on to modern people.

Two significant international studies involving hundreds of scientists, including a human geneticist at the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest that specific cells in the human nasal passage shaped like a champagne glass, known as goblet cells, may play a significant role in enabling COVID-19 infections.

The ability to genetically modify organisms via means such as the CRISPR/Cas9 gene-editing technology is changing our approach to pest control. A new study published in The CRISPR Journal outlines one team's efforts in developing a novel CRISPR/Cas9 gene-editing protocol that could help in efforts to control the whitefly pest.

Different groups of bats have their own unique strains of coronavirus.

Researchers have discovered antibodies that trigger a “kill switch” in malarial cells, causing them to self-destruct.

A first-in-human trial of a vaccine against “MERS” (Middle East Respiratory Syndrome) has been conducted, and offers lessons and insights for the development of a SARS-CoV-2 vaccine.

Researchers report that they have been able to restore sensation to the hand of a research participant with a severe spinal cord injury using a brain-computer interface (BCI) system.