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Novel Cellular Entry Factor for Viral Vectors Used in Gene Therapy
Researchers led by a team at Massachusetts Eye and Ear have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types--the most commonly used viral vectors for in vivo gene therapy. AAVs are vectors-or vehicles--that are created from a virus that is made harmless by molecular engineering, and have shown promise transporting genetic therapy treatments to affected tissues.
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How Can We Prompt Individuals To Take Action on Climate Change?
A researcher has combined two decades of scientific studies on climate change in order to pinpoint the obstacles to behavior change and find ways to overcome them.
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A New Component of Blood Is Revealed
Scientists have revolutionized knowledge of the mitochondria organelle by revealing that whole functioning extracellular mitochondria are in fact found in the bloodstream.
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Lowering Salt Consumption Not Linked to Weight Gain
Well-controlled study of more than 400 participants supports reducing salt intake as an important public health strategy to decrease incidence of hypertension, and debunks the notion that it contributes to weight gain.
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Vaccine for African Swine Fever Virus Shows Promise
Government and academic investigators have developed a vaccine against African swine fever that appears to be far more effective than previously developed vaccines.
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Lessons From Previous Outbreaks of Coronavirus Could Inform Current Measures
The new cluster of viral pneumonia cases originating in Wuhan, China, marks the third time in 20 years that a member of the large family of coronaviruses (CoVs) has jumped from animals to humans and sparked an outbreak. We look back at two earlier novel CoV outbreaks that initially caused global havoc and describe steps needed to contain the current one.
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Liver Fibrosis “Off Switch” Could Help Fight Alcoholic Liver Disease
Understanding the process of liver fibrosis, could help researchers develop new ways to prevent or treat conditions such as alcoholic liver disease. A team has now demonstrated for the first time that liver fibrosis progression could potentially be targeted by manipulating a special population of liver cells.
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Immune Cells Aid Invasion of Brain Tumors
A team has analyzed the role of immune cells in the expansion of glioblastoma, a type of aggressive brain tumor.
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Taking Aim at Gastric Cancer
A team has discovered that a novel drug, called “FerriIridium”, is capable of simultaneously diagnosing and treating gastric cancer.
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Curvy Cancer-causing Bacterium "Keeps in Shape”
New insights into how the cancer-causing stomach bacterium keeps its shape could pave the way for the creation of more-specialized antibiotics.
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