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Popular Antidepressant Drug Rewires the Brain, in Mouse Model
Prozac®, the trade name for the drug fluoxetine, was introduced to the U.S. market for the treatment of depression in 1988. Researchers report that, in addition to the drug’s known action on serotonin receptors, fluoxetine could rearrange nerve fibers in the hippocampus of mouse brains.
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Larger, Earlier Drug Trials Needed to Fight Alzheimer's
There are currently no drugs that stop or inhibit Alzheimer's disease. Despite drug trials showing plaque reduction in the brain, the patients' cognitive function did not improve. Would the results be different if it were possible to design studies that intervene much earlier on in the disease, before cognition is affected?
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ID1 Protein: A Potential Target in Glioblastoma
A new study suggests the protein ID1 is critical to tumor initiation and growth and also impacts glioblastoma's response to chemotherapy. Researchers are hopeful that new strategies could emerge from these findings that could help slow the growth and re-occurrence of this brain cancer.
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Creating a Human Liver Cell Atlas
Despite the immense importance of the liver for human health, the diversity of individual liver cell types and the associated molecular and cellular processes in both healthy and diseased tissue have not yet been fully investigated, until now.
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Expert Mathematicians Stumped by Simple Subtractions
Researchers have demonstrated that our ability to solve mathematical problems is influenced by non-mathematical knowledge, which often results in mistakes. The findings indicate that high-level mathematicians can be duped by some aspects of their knowledge about the world and fail to solve primary school-level subtraction problems.
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Impaired Learning Linked to Having a First-degree Relative With Alzheimer’s Disease
Adults with a first-degree relative with Alzheimer's disease perform more poorly on online paired-learning tasks than adults without such a family history, and this impairment appears to be exacerbated by having diabetes or a genetic variation in the apolipoprotein E (APOE) gene linked to the disease.
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20-Year-Long Study Shows Common Butterfly Species Is on the Decline
The most extensive and systematic insect monitoring program ever undertaken in North America shows that butterfly abundance in Ohio declined yearly by 2%, resulting in an overall 33% drop for the 21 years of the program.
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Higher Consumption of Sugary Drinks May Increase Risk of Cancer
A new study reports a possible association between higher consumption of sugary drinks and and an increased risk of cancer, supporting existing recommendations to limit sugary drink consumption.
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Secrets of Sex Switching Fish Are Revealed
We may take it for granted that the sex of an animal is established at birth and doesn't change. However, about 500 species of fish change sex in adulthood, often in response to environmental cues. How these fish change sex has, until now, been a mystery.
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What You Do When Bored is Important to Your Mental Health
Boredom is a common human experience. But how people cope with or handle being bored is important for mental health. The brains of people who are prone to boredom react differently, compared to those who don't, Perone and his colleagues found in a new paper recently published in the journal Psychophysiology.
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