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A team led by researchers from Broad Institute of MIT and Harvard, and the McGovern Institute for Brain Research at MIT, has characterized and engineered a new gene-editing system that can precisely and efficiently insert large DNA sequences into a genome.

In 1981, a patient from Sydney was transfused with a weakened form of HIV-1 when he received a blood transfusion following a motorbike accident. After controlling his infection for more than 30 years, he appears to have cleared his infection altogether – without therapy.

In an analysis of the real-world impact of a pioneering test called metagenomic next-generation sequencing (mNGS), developed by UCSF scientists to diagnose patients with mysterious inflammatory neurological conditions, the technique was shown to identify infections better than any standard clinical method.

A new study suggests that the surveys routinely used to understand how people use their smartphone are poorly related to actual smartphone use when measured with an app. Researchers say this means that existing evidence suggesting that screen time is “addictive” cannot be used to justify any change of policy.

Researchers report that a brain-computer interface, a form of artificial intelligence, can sense when its user is expecting a reward by examining the interactions between single-neuron activities and the information flowing to them. The findings potentially have applications for robotic prosthetics, which would sense what a user wants to do (pick up a glass, for example) and do it.

Scientists in the United States, Europe and South America are reporting how a new cloud-computing web platform allows scientists to track data and analyses on the brain, potentially reducing delays in discovery.

Predicting what someone's face looks like based on a DNA sample remains a hard nut to crack for science. It is, however, getting easier to use such a sample to filter the right face from a face database.

Understanding the intricate structure of the outer layer of noroviruses (the caspid) could help in vaccine development for the leading cause of food-borne illness outbreaks.

Researchers have reported the successful, long-term relief of chronic pain in a wheelchair user with spinal cord injury following a single injection of adipose tissue into the affected shoulder joint. This is the first reported use of this intervention for shoulder pain in an individual with spinal cord injury who has failed to improve with conservative care, such as physical therapy.

Removal of introns from pre-mRNAs is an essential step in eukaryotic gene expression. Using yeast, researchers provided new insights on this evolutionarily conserved quality assurance step.