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Room for Thought

To move through the world, you need a sense of your surroundings, especially of the constraints that restrict your movement: the walls, ceiling and other barriers that define the geometry of the navigable space around you. And now, a team of neuroscientists has identified an area of the human brain dedicated to perceiving this geometry
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Decade’s Worth of Research Outlines How Mutations Lead to Degenerative Disease

Scientists have discovered how mutations in DNA can cause neurodegenerative disease. The discovery is an important step towards better treatment to slow the progression or delay onset in a range of incurable diseases such as Huntington’s and motor neurone disease – possibly through the use, in new ways, of existing anti-inflammatory drugs.
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Radiotherapy System Rotates Patients in Sync With X-Ray Beam To Deliver Accurate Treatment for Brain Cancer

A new way to deliver radiotherapy that rotates patients in sync with the treatment beam could treat patients with brain cancer as accurately and quickly as the most advanced radiotherapy available, scientists at The Institute of Cancer Research, London show.
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One Type of Bone Cell Can Subdue Cancer Metastases

A subpopulation of bone cells releases factors that can halt the growth of breast cancer has traveled to the bone, putting the cells in stasis.
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Bacteria Could Help Combat Pesticide Resistance in Insects

Research into an intricate toxin delivery system found in bacteria could overcome the problem of pesticide resistance in insects, and might even lead to new cancer treatments.
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Cancer Cell Chromosome Count Could Clarify Prognosis

For decades, biologists have also known that cancer cells often have too few or too many copies of some chromosomes, a state known as aneuploidy. In a new study of prostate cancer, researchers have found that higher levels of aneuploidy lead to much greater lethality risk among patients.
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The Connectivity "Fingerprint" of Psychosis

Researchers studying large-scale systems in the brain have published findings that could improve understanding of the symptoms and causes of bipolar disorder, schizophrenia, depression, and other mental illnesses.
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Organ Chip Facilitates Human Gut Microbiome Studies

The anaerobic human Intestine chip supports complex gut microbiome under low oxygen, enabling direct investigations of health and disease-related human-microbiome interactions.
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Tomato Pan-genome Makes Bringing Flavor Back Easier

Almost everyone agrees that store-bought tomatoes don't have much flavor. Now, scientists may have spotlighted the solution after constructing the pan-genome for the cultivated tomato and its wild relatives.
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Catch a Virus by Its Tail

Research by scientists at Harvard Medical School's Blavatnik Institute yields a surprising answer: The viral machinery in charge of this survival-ensuring maneuver becomes activated by an RNA from the opposite end of the segment where copying starts. The findings, published May 9 in PNAS, identify new potential targets to inhibit the replication of segmented viruses.
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