News

Aptamer Therapeutics Limited is pleased to announce a new collaboration with Dan Wiseman and the Oglesby Leukaemia Research Programme at the University of Manchester and Cancer Research UK. The project will explore the potential of aptamers as therapeutic agents for the treatment of chronic myelomonocytic leukemia and other myeloid malignancies.

Experimental and clinical evidence presents new reasons why about half of patients whose tumors are marked by a large number of mutations from "mismatch repair genetic deficiency" fail to respond to immunotherapy.

Scientists have found significant differences in the shape and biology of the same type of cell taken from different parts of the retina. The results could help explain why the macular region of the eye is more susceptible to disease than the peripheral retina and reveals a protective mechanism that may be disrupted in disease.

How can high school students learn about a technology as complex and abstract as CRISPR? It's simple: just add water.

Researchers have developed an integrated synthetic biology system to construct new metabolic pathways and enzymes within microbes. By incorporating a "Design, Build, Test, Learn" (DBTL) workflow, the production of pharmaceutical raw materials could be systematically optimized.

Induced pluripotent stem cells can make tiny “cargo packets” that are able to deliver potentially restorative or repairing proteins, antibodies or other therapies to aged cells.

Blocking the action of an enzyme involved in protein digestion may improve metabolic health, according to a new study.

Researchers found that electroconvulsive therapy corrects brain networks associated with learning and thinking impairments.

A retrospective review of people with fibromyalgia revealed insights into a possible pathogenic relationship between fibromyalgia and insulin resistance. Those who had undergone treatment with metformin, a medicine used to treat type 2 diabetes, reported dramatic improvements of their pain after treatment.

For people with depression, gastrointestinal distress is a common additional burden, and a new study suggests that for some, the two conditions arise from the same glitch in neuron chemistry--low serotonin. The study, conducted in mice, shows that a shortage of serotonin in the neurons of the gut can cause constipation, just as a serotonin shortage in the brain can lead to depression.