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Potential Marker of Preterm Babies at Risk of Cerebral Palsy
Preterm babies born without haptoglobin, a protein in blood cells, have higher odds of brain bleeding, cerebral palsy and death.
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A Call for Greater Diversity Within Genetic Data Sets
According to a new study, polygenic scores developed by studying Europeans do a better job at predicting disease risk for people of European ancestry than for those of other ancestries.
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Progress Towards Personalized Cancer Immunotherapy
Medicine has great hopes for personalized cancer immunotherapy. The idea is to have a vaccine prompt the immune system to fight a tumor. Scientists at ETH Zurich have developed a method that allows them to determine which molecules are suited to patient-specific immunization.
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Promising New Drugs for an Old Pathogen
Tuberculosis (TB), an ancient and notoriously difficult disease to treat, has killed millions through the course of human history; and the antibiotics that have been used to fight the disease in recent history are becoming less and less effective. In the face of this reality, researcher Prof. Dennis Wright has improved upon a new way to thwart the tricky pathogen, mycobacterium tuberculosis.
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A Targetable Vulnerability in Breast Cancer Cells
Researchers at the University of Helsinki and Karolinska Institutet have discovered new molecular mechanisms of breast cancer cell signaling that contribute to aggressive behavior of cancer cells.
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Rare Genes Linked to Alzheimer Disease for the First Time
Researchers have identified two, extremely rare genetic variants linked to Alzheimer disease (AD) for the first time. These variants, one located in the NOTCH3 gene and the other in the TREM2 gene, were observed in persons with AD but not in any of the controls.
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What Big Data Reveals About the Diversity of Species
"Big data" and large-scale analyses are critical for biodiversity research. The necessary data may come from many sources: museum collections, biological literature, and local databases. Researchers have investigated how this wealth of knowledge can best be integrated so that it can be transported into the digital age and used for research.
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Novel Brain Map Tracks Early Brain Atrophy From HIV Infection
A new map of brain tissue in people with HIV shows atrophy in several areas including a primary neurocognitive control center where shrinkage and loss of function can be seen in scans before clinical symptoms appear.
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Movement Toward a Poop Test for Liver Cirrhosis
In a study of people with nonalcoholic fatty liver disease and their twins and other close relatives, UC San Diego researchers were able to diagnose liver cirrhosis simply by analyzing a person’s stool microbes
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Simplified Synthesis
For the first time, researchers discovered a simple and highly efficient way to produce certain kinds of organic compounds. This could have huge implications for industries such as pharmaceuticals, petrochemicals, materials and more.
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