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Precise Informatics Platform Targets Tau Tangles

Researchers have developed an artificial intelligence platform to detect a range of neurodegenerative diseases in human brain tissue samples, including Alzheimer’s disease and chronic traumatic encephalopathy. Their discovery will help scientists develop targeted biomarkers and therapeutics, resulting in a more accurate diagnosis of complex brain diseases.
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Beware of Sleeping Queens Underfoot This Spring

It was long thought that queen bumblebees, after hibernating in the ground over winter, emerged, began feeding and dispersed quite quickly to found their new colony. However, new reports of queen bumblebee behavior suggests otherwise.
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Hidden Differences Between CTE and Alzheimer's Identified

There has been a long-held hypothesis stating that chronic traumatic encephalopathy and Alzheimer’s disease tau tangles were made in the same way. However, a study utilizing cryo-electron microscopy has revealed a very different picture.
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Drug Designed to Treat Opioid Cravings Begins Clinical Trial Testing

Researchers at the University of Maryland School of Medicine (UMSOM) Institute of Human Virology (IHV) are collaborating with scientists at the National Institutes of Health to test an experimental drug to curb opioid cravings.
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Plant Immunity Cut to Size

Researchers have found a link between a class of enzymes and immune signals that is rapidly triggered upon physical damage in plants.
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Whetstone Sharpens Up Artificial Neurons

Whetstone, a software tool that sharpens the output of artificial neurons, has enabled neural computer networks to process information up to a hundred times more efficiently than the current industry standard, say the Sandia National Laboratories researchers who developed it.

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European Bioinformatics Institute Launches Protein Data Bank

EMBL’s European Bioinformatics Institute (EMBL-EBI) and collaborators have launched a new data resource, called Protein Data Bank in Europe Knowledge Base (PDBe-KB), which gives researchers a more comprehensive view of publicly available protein structure data.
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Exploring the Evolution of Brain Tumors

Scientists from the German Cancer Research Center found in a recent study that only three different genetic alterations drive the early development of malignant glioblastomas.
Distinguishing Feature of T Cells in Colorectal Tumors Identified content piece image
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Distinguishing Feature of T Cells in Colorectal Tumors Identified

High-dimensional mass cytometry has been used to characterize cells in the tumors of people with bowel cancer, revealing activated regulatory T cells as a defining feature.
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Topical Immunotherapy Lowers Risk of Skin Cancer

A combination of two topical creams already shown to clear precancerous skin lesions from sun-damaged skin also lowers the risk that patients will later develop squamous cell carcinoma of the skin.
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