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Lupus Linked to Gut Microbiome Imbalances
Lupus -marked by an attack on joints, skin, and kidneys by the body’s immune system - has been linked to an abnormal mix of bacteria in the gut.
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A Solution for Pollen Allergies?
Birch pollen allergic rhinitis is the most common chronic disorder in the Northern part of the globe, and it attributes to significant morbidity and economic burden. According to a new study, pollen allergen immunotherapy has favorable effects on the molecular events and microbiome profile in the nasal membrane.
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The When and Where of Walking in the Brain
In order to understand how the brain learns new locomotor patterns, researchers developed a split-belt treadmill for mice. This allowed them to manipulate neural activity in specific populations of neurons to test their role in locomotor learning. The team demonstrated that mice learn in a way that is very similar to humans, and revealed insights into how the brain makes this learning happen.
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Cracking a One-Two Punch Against Melanoma
Updated, safer versions of diphtheria fusion toxin DAB-IL-2 show promise in reducing tumor growth.
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Land Use Changes Insufficient to Combat Global Warming
Previous measures to reduce global warming through land use change are insufficient.
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A New Map of the Brain's Immune System
A team of researchers has created an entirely new map of the brain's own immune system in humans and mice. The scientists succeeded in demonstrating for the first time ever that the phagocytes in the brain, the so-called microglia, all have the same core signature but adopt in different ways depending on their function. It was previously assumed that these are different types of microglia.
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Blueprint Guides Treatment of Deadly Brain Tumor
In a study of mice and human brain tumors researchers searched for new treatments by exploring the reasons why some patients with gliomas live remarkably longer than others. The results suggested that certain patients’ tumor cells are less aggressive and much better at repairing DNA than others but are difficult to kill with radiation.
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Improving Diagnosis of Bacterial Infections in Infants
A new protocol could help ER physicians to rule out life-threatening bacterial infections among infants up to 2 months of age who have fevers, potentially eliminating the need for unnecessary treatments.
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New Machine Learning Method Could Prevent Unnecessary Breast Surgery
Researchers have found a machine learning method that can predict the likelihood that a high-risk type of breast lesion is cancerous, potentially saving some women from unnecessary surgeries and overtreatment.
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Genetic Influences on Body Fat Distribution
A new breakthrough identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue.
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